Bazhan N M, Krass P M, Osadchuk L V
Probl Endokrinol (Mosk). 1978 May-Jun;24(3):70-4.
Interaction between the hypophysial-adrenal system (HAS) and the hypophysis-gonad system was studied. For this purpose the foxes were subjected to total gonadectomy 8 months before they were sacrificed. Functional activity of the HAS was judged by the hypophysis ACTH content, corticosteroid production by the adrenal cortex in vitro, and by the glucocorticoid concentration in the peripheral blood. Castration of male foxes foxes failed to influence the activity of various HAS links. Gonadectomy of females was accompanied by changes in the activity of individual HAS links in different direction--some reduction of ACTH in the hypophysis, a sharp and significant fall of the peripheral blood glucocorticoid level and a marked significant elevation of hydrococortisone production in the adrenal cortex in vitro.
对垂体-肾上腺系统（HAS）与垂体-性腺系统之间的相互作用进行了研究。为此，在处死狐狸前8个月对其进行双侧性腺切除术。通过垂体促肾上腺皮质激素（ACTH）含量、肾上腺皮质体外皮质类固醇生成以及外周血中糖皮质激素浓度来判断HAS的功能活性。雄性狐狸去势对HAS各个环节的活性没有影响。雌性狐狸去势后，HAS各个环节的活性出现不同方向的变化——垂体中ACTH有所降低，外周血糖皮质激素水平急剧且显著下降，肾上腺皮质体外氢化可的松生成显著升高。
