NIH Epigenomics Roadmap Data Analysis and Coordination Center, Molecular and Human Genetics Department, Baylor College of Medicine, Houston, Texas, USA.
Nat Biotechnol. 2010 Oct;28(10):1053-6. doi: 10.1038/nbt1010-1053.
Comparative analysis of epigenomes offers new opportunities to understand cellular differentiation, mutation effects and disease processes. But the scale and heterogeneity of epigenetic data present numerous computational challenges.
比较基因组分析为理解细胞分化、突变效应和疾病过程提供了新的机会。但是,表观基因组数据的规模和异质性带来了许多计算挑战。