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[巴西圣保罗州博图卡图市学童沙眼的患病率及空间分布]

[Prevalence and spatial distribution of trachoma among schoolchildren in Botucatu, São Paulo - Brazil].

作者信息

Schellini Silvana Artioli, Lavezzo Marcelo Mendes, Ferraz Lucieni Barbarini, Olbrich Neto Jaime, Medina Norma Hellen, Padovani Carlos Roberto

机构信息

Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Botucatu, SP, Brasil.

出版信息

Arq Bras Oftalmol. 2010 Jul-Aug;73(4):358-62. doi: 10.1590/s0004-27492010000400012.

Abstract

PURPOSE

To assess the prevalence of trachoma in schoolchildren of Botucatu/ SP-Brazil and its spatial distribution.

METHODS

Cross-sectional study in children aged from 7 to 14 years, who attended elementary schools in Botucatu/SP in November/2005. The sample size was estimated in 2,092 children, considering the 11.2% historic prevalence of trachoma, accepting an estimation error of 10% and confidence level of 95%. The sample was random, weighted and increased by 20%, because of the possible occurrence of losses. The total number of children examined was 2,692. The diagnosis was clinical, based on WHO guidelines. For the evaluation of spatial data, the CartaLinx program (v1.2) was used, and the school demand sectors digitized according to the planning divisions of the Department of Education. The data were statistically analyzed, and the analysis of the spatial structure of events calculated using the Geode program.

RESULTS

The prevalence of trachoma in schoolchildren of Botucatu was 2.9% and there were cases of follicular trachoma. The exploratory spatial analysis failed to reject the null hypothesis of randomness (R= -0.45, p>0.05), with no significant demand sectors. The analysis for the Thiessen polygons also showed that the overall pattern was random (I= -0.07, p=0.49). However, local indicators pointed to a group of low-low type for a polygon to the north of the urban area.

CONCLUSION

The prevalence of trachoma in schoolchildren in Botucatu was 2.9%. The analysis of the spatial distribution did not reveal areas of greater clustering of cases. Although the overall pattern of the disease does not reproduce the socio-economic conditions of the population, the lower prevalence of trachoma was found in areas of lower social vulnerability.

摘要

目的

评估巴西圣保罗州博图卡图市学童沙眼的患病率及其空间分布情况。

方法

对2005年11月在圣保罗州博图卡图市小学就读的7至14岁儿童进行横断面研究。考虑到沙眼11.2%的历史患病率,接受10%的估计误差和95%的置信水平,样本量估计为2092名儿童。由于可能出现失访情况,样本采用随机、加权并增加20%的方式选取。总共检查了2692名儿童。诊断依据世界卫生组织的指南进行临床诊断。为评估空间数据,使用了CartaLinx程序(v1.2版),并根据教育部的规划分区将学校需求区域数字化。对数据进行统计分析,并使用Geode程序计算事件的空间结构分析。

结果

博图卡图市学童沙眼患病率为2.9%,且存在滤泡性沙眼病例。探索性空间分析未能拒绝随机性的零假设(R = -0.45,p>0.05),未发现有显著差异的需求区域。泰森多边形分析也表明总体模式是随机的(I = -0.07,p = 0.49)。然而,局部指标显示市区北部的一个多边形呈现低-低类型组。

结论

博图卡图市学童沙眼患病率为2.9%。空间分布分析未发现病例聚集程度较高的区域。尽管该疾病的总体模式并未反映出人群的社会经济状况,但在社会脆弱性较低的地区发现沙眼患病率较低。

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