Cogn Neuropsychol. 2001 Jul 1;18(5):385-410. doi: 10.1080/02643290126060.
We report a cognitive investigation of a case of deep dysphasia appearing in the context of primary progressive aphasia. Over a period of 5 years, patient CO presented progressive difficulties in word finding and in oral comprehension, while nonverbal cognitive functions remained preserved. As in other deep dysphasic patients, CO's repetition performance showed marked imageability and lexicality effects, and semantic paraphasias. The same effects were observed in writing-to-dictation. Regularisation errors occurred in word reading. CO's short-term memory span was less than two words. A cognitive analysis of language processing revealed difficulties in phoneme identification and rhyme judgement, in detecting grammatical class for orally presented words, and in oral and written naming. The interpretation of CO's deep dysphasic symptoms within interactive models of language processing confirmed the importance of a phonological short-term storage impairment as an explanatory factor of deep dysphasia.
我们报告了一例原发性进行性失语症背景下出现的深度构音障碍的认知研究。在 5 年的时间里,患者 CO 逐渐出现了找词和口头理解的困难,而非语言认知功能保持完好。与其他深度构音障碍患者一样,CO 的重复表现出明显的形象性和词汇性效应,以及语义错语。在听写中也观察到了同样的效果。在单词阅读中出现了规则化错误。CO 的短期记忆跨度小于两个单词。对语言处理的认知分析显示,在识别音位和押韵判断、检测口头呈现单词的语法类别、口头和书面命名方面存在困难。在语言处理的互动模型中对 CO 的深度构音障碍症状的解释证实了语音短期存储损伤作为深度构音障碍的解释因素的重要性。