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研究中的利益冲突:临床决策是否受到损害?一篇观点论文。

Conflicts of interest in research: is clinical decision-making compromised? An opinion paper.

作者信息

Adibi Shawn, Bebermeyer Richard D

机构信息

University of Texas Health Science Center at Houston Dental Branch, USA.

出版信息

Tex Dent J. 2010 Aug;127(8):735-41.

Abstract

Lack of transparency in funded research can compromise clinical decision-making in an evidence-based practice. Transparency can be defined as full disclosure of all financial assistance and support to authors and investigators. There is a perception that ethical principles are eroding and that research data can be biased due to conflicts of interest. These research outcomes biased or not, are used for clinical decision-making in the evidence-based practice. One suggested solution to this common ethical dilemma is to continue the dialogue on transparency in research and to create oversight bodies which include representatives from business and industry, private practice, academia, and research. There is increasing evidence of the need for more ethics education at all levels.

摘要

资助研究缺乏透明度可能会损害循证实践中的临床决策。透明度可定义为向作者和研究者全面披露所有资金援助和支持。有一种观点认为,道德原则正在受到侵蚀,并且由于利益冲突,研究数据可能存在偏差。这些研究结果无论有无偏差,都被用于循证实践中的临床决策。针对这一常见道德困境,一个建议的解决方案是继续就研究透明度进行对话,并设立监督机构,其中包括来自商业、行业、私人执业、学术界和研究领域的代表。越来越多的证据表明,各级都需要加强伦理教育。

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