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[癫痫发作作为颅内肿瘤的首发症状。一项针对成年人的前瞻性研究]

[Epileptic seizures as initial symptom of intracranial tumors. A prospective study in adults].

作者信息

Vasconcelos D

机构信息

Instituto Nacional de Neurología y Neurocirugía. Secretaría de Salud.

出版信息

Gac Med Mex. 1990 May-Jun;126(3):169-74; discussion 174.

PMID:2094618
Abstract

A prospective study of 125 patients with late-onset epileptic crisis: Group G I with 65 cases between 20 and 50 years of age, and Group G II, including 60 patients older than 50 years at the time of the first crisis. Brain tumors were diagnosed in fourteen cases, four (6.1%) in G I and ten (16.6%) in G II. In decreasing order of frequency, the ictal pattern was tonic-clonic, status epilepticus, partial simple, partial complex and "drop-attacks". The lesions were located as follows:frontal in seven subjects, parietal in four, multiple in two and temporo-basal in one. Histologically, the tumors were three meningiomas, two gliomas, one astrocytoma, and three metastatic lesions. These findings agree with those of other series, in terms of predominant type of crisis, site and histologic type; but they differ in the age of first symptoms, and in the fact that tumors occupy only a third place as cause of epileptic crisis.

摘要

一项对125例迟发性癫痫发作患者的前瞻性研究:G I组有65例年龄在20至50岁之间,G II组包括60例首次发作时年龄超过50岁的患者。14例诊断为脑肿瘤,G I组4例(6.1%),G II组10例(16.6%)。按发作频率从高到低依次为强直阵挛发作、癫痫持续状态、部分性单纯发作、部分性复杂发作和“跌倒发作”。病变部位如下:额叶7例,顶叶4例,多发2例,颞叶底部1例。组织学上,肿瘤包括3例脑膜瘤、2例胶质瘤、1例星形细胞瘤和3例转移瘤。在主要发作类型、部位和组织学类型方面,这些发现与其他系列研究一致;但在首次症状出现的年龄以及肿瘤仅占癫痫发作病因第三位这一事实上存在差异。

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