Cedars-Sinai/University of California at Los Angeles, Beverly Hills, California, USA.
Ann N Y Acad Sci. 2011 Feb;1218:33-7. doi: 10.1111/j.1749-6632.2010.05769.x. Epub 2010 Sep 28.
Bisphosphonates are the gold standard of treatment of postmenopausal osteoporosis, male osteoporosis, and steroid-induced osteoporosis. They have potential use in multiple musculoskeletal conditions other than osteoporosis and have also been shown to treat Paget's disease of the bone and osteogenesis imperfecta. Bisphophonates may have potential use in periprosthetic bone loss, osteonecrosis of the hip, fibrous dysplasia, and calcinosis in juvenile dermatomyositis.
双膦酸盐是绝经后骨质疏松症、男性骨质疏松症和类固醇诱导性骨质疏松症的治疗金标准。它们在骨质疏松症以外的多种肌肉骨骼疾病中有潜在的用途，并且已经被证明可以治疗骨 Paget 病和骨发育不全。双膦酸盐在假体周围骨丢失、髋关节骨坏死、纤维发育不良和青少年皮肌炎中的钙沉积症中可能有潜在的用途。
Ann N Y Acad Sci. 2010-9-28
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