Ma Wenlin, Hu Dayi, Liu Guanghui, Jiang Jinfa, Zhao Xudong, Ma Yunsheng
Department of Cardiology, Tongji Hospital of Tongji University, Putuo District, Shanghai, China.
Asian Cardiovasc Thorac Ann. 2010 Oct;18(5):469-75. doi: 10.1177/0218492310381291.
Predictors of quality of life in Chinese patients with acute coronary syndrome remain unknown. Between January 2006 and March 2009, a prospective cohort study of 782 patients with acute coronary syndrome was carried out, with follow-up 7 months later. Depression and anxiety symptoms were measured using the Hospital Anxiety and Depression Scale. Quality of life was assessed using the 36-Item Short-Form Health Survey. To identify predictors of decreased quality of life, both the physical and mental component summary scores were analyzed using multiple and ordinal logistic regression. In our quality-of-life model, diabetes mellitus was an independent risk factor for a low mental component summary score. Anxiety symptoms and the baseline mental component summary score were significant independent predictors of a low mental component summary score. Acute myocardial infarction was found to be a risk factor for a low physical component summary score. Anxiety symptoms, baseline physical component summary score, and systolic blood pressure on admission were significant independent predictive factors. Among patients with acute coronary syndrome, those with acute myocardial infarction, diabetes, or a low baseline quality of life need more care and effective intervention to improve their quality of life.
中国急性冠状动脉综合征患者生活质量的预测因素尚不清楚。2006年1月至2009年3月，对782例急性冠状动脉综合征患者进行了一项前瞻性队列研究，并在7个月后进行随访。使用医院焦虑抑郁量表测量抑郁和焦虑症状。使用36项简短健康调查问卷评估生活质量。为了确定生活质量下降的预测因素，使用多元和有序逻辑回归分析了身体和心理成分汇总得分。在我们的生活质量模型中，糖尿病是心理成分汇总得分低的独立危险因素。焦虑症状和基线心理成分汇总得分是心理成分汇总得分低的显著独立预测因素。发现急性心肌梗死是身体成分汇总得分低的危险因素。焦虑症状、基线身体成分汇总得分和入院时的收缩压是显著的独立预测因素。在急性冠状动脉综合征患者中，患有急性心肌梗死、糖尿病或基线生活质量低的患者需要更多的护理和有效的干预措施来提高他们的生活质量。
