Postgraduate Program, Oral Pathology, Federal University of Rio Grande do Norte, CEP: 59056-000, Natal, RN, Brazil.
Ann Diagn Pathol. 2011 Feb;15(1):6-11. doi: 10.1016/j.anndiagpath.2009.12.009. Epub 2010 Mar 17.
Sialolipoma is a recently described histologic variant of lipoma and is characterized by well-demarcated proliferation of mature adipocytes with secondary entrapment of salivary gland elements. These tumors have been observed in both the major and minor salivary glands, with more than 20 cases being reported in the English literature. In general, the clinical presentation of sialolipomas of the minor salivary glands suggests a diagnostic hypothesis of salivary gland lesions, commonly neoplasms. In the major salivary glands, the clinical features suggest either a salivary gland neoplasm or a lipoma. Surgical excision is the treatment of choice for sialolipomas, with no reports of recurrence or malignant transformation. The present article reports 4 additional cases of sialolipoma, all of them affecting the minor salivary glands, and reviews the literature regarding clinicopathologic aspects, differential diagnosis, and therapeutic management of this recently recognized histologic variant of lipoma.
涎脂瘤是一种新近描述的脂肪瘤组织学变异型，其特征是成熟脂肪细胞界限清楚地增殖，其次是涎腺成分的捕获。这些肿瘤已在大、小涎腺中观察到，英文文献中有 20 多个病例报道。一般来说，小涎腺涎脂瘤的临床表现提示涎腺病变的诊断假设，通常为肿瘤。在大涎腺中，临床特征提示涎腺肿瘤或脂肪瘤。手术切除是涎脂瘤的首选治疗方法，无复发或恶性转化的报道。本文报告了 4 例额外的涎脂瘤病例，均发生于小涎腺，并复习了有关这种新近认识的脂肪瘤组织学变异型的临床病理特征、鉴别诊断和治疗管理的文献。
