Kaplan N M
University of Texas Southwestern Medical Center, Dallas 75235-8899.
J Hypertens Suppl. 1990 Dec;8(7):S175-9.
The increasing tendency to treat hypertension has markedly reduced stroke mortality but has not significantly reduced the mortality from coronary heart disease. Many explanations for this failure have been proposed and the true reason may never be known. Nevertheless, a number of steps can be taken to improve the degrees of therapeutic protection against coronary heart disease including (1) a complete assessment of all alterable risk factors; (2) effective use of multiple non-drug therapies; (3) use of antihypertensive drugs that reduce other cardiovascular risk factors; and (4) a gradual reduction of blood pressure to levels that will preserve perfusion to vital organs.
治疗高血压的趋势日益增加，这显著降低了中风死亡率，但并未显著降低冠心病死亡率。针对这一失败提出了许多解释，真正原因可能永远无法得知。然而，可以采取一些措施来提高对冠心病的治疗保护程度，包括：（1）全面评估所有可改变的风险因素；（2）有效使用多种非药物疗法；（3）使用能降低其他心血管风险因素的降压药物；（4）将血压逐渐降至能维持重要器官灌注的水平。
