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评估 RBANS 视觉和言语指数在神经损伤老年参与者样本中的应用。

Assessment of the RBANS Visual and Verbal Indices in a sample of neurologically impaired elderly participants.

机构信息

Department of Psychiatry & Behavioral Sciences,University of Oklahoma Health Sciences Center, Oklahoma City, OK 73126, USA.

出版信息

Clin Neuropsychol. 2010 Nov;24(8):1365-78. doi: 10.1080/13854046.2010.516769. Epub 2010 Oct 15.

Abstract

With increases in the older adult population, brief assessments sensitive to dementia are essential. This study assessed the effectiveness of the verbal memory and visual processing indices proposed by Duff et al. (2009) to differentiate participants with neurological disorders. Participants included individuals diagnosed with mild cognitive impairment (MCI; n = 38), Alzheimer's disease (AD; n = 100), or Parkinson's disease (PD; n = 35), with ages ranging from 65-93 years. In addition, normal control participants (n = 100) within the same age range were used for comparison. ANOVA and posthoc analyses revealed that the normal control and AD groups were significantly different from all groups for Verbal and Visual Indices. However, the MCI and PD groups did not differ from each other. Predictive discriminant analysis (PDA) assessed classification rates of the groups, and the normal participants were classified best (63% to 92%). The AD group followed with percentages ranging from 64% to 76%. Specifically, when classifying the normal and AD groups using both Verbal and Visual Indices of the RBANS together, sensitivity was 92.0% (n = 92) and specificity was 79.0% (n = 79). Overall classification rates for this analysis were 85.5%. Overall, the RBANS Verbal and Visual Indices may provide additional information when working with neurologically impaired older adults, with overall classification rates ranging from 61.5% to 85.5%.

摘要

随着老年人口的增加,对痴呆症敏感的简短评估至关重要。本研究评估了 Duff 等人(2009 年)提出的言语记忆和视觉处理指标在区分神经障碍患者方面的有效性。参与者包括被诊断为轻度认知障碍(MCI;n = 38)、阿尔茨海默病(AD;n = 100)或帕金森病(PD;n = 35)的个体,年龄在 65-93 岁之间。此外,还使用了相同年龄范围内的 100 名正常对照组参与者进行比较。方差分析和事后分析表明,正常对照组和 AD 组在言语和视觉指标上与所有组均有显著差异。然而,MCI 和 PD 组彼此之间没有差异。预测判别分析(PDA)评估了各组的分类率,正常组的分类准确率最高(63%至 92%)。AD 组的准确率范围为 64%至 76%。具体来说,当使用 RBANS 的言语和视觉指数联合对正常和 AD 组进行分类时,灵敏度为 92.0%(n = 92),特异性为 79.0%(n = 79)。该分析的总体分类率为 85.5%。总的来说,RBANS 的言语和视觉指数在为神经受损的老年人提供信息方面可能会提供额外的信息,其总体分类率为 61.5%至 85.5%。

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