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[91例囊性棘球蚴病患者术后的临床、血清学及形态学分析]

[The clinical, serological and morphological analysis of 91 patients with cystic echinococcosis following surgery].

作者信息

Mıman Ozlem, Atambay Metin, Aydin Nasuhi Engin, Daldal Nilgün

机构信息

Afyon Kocatepe Üniversitesi Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Afyonkarahisar, Türkiye, Turkey.

出版信息

Turkiye Parazitol Derg. 2010;34(3):179-83.

Abstract

Cystic echinococcocis (CE) is a zoonotic infection caused by metacestod form of Echinococcus granulosus. In this study, 91 patients with CE were revealed according to their gender, age, symptoms, cyst localization and size, and also to their preoperative serologic analysis results. These patients were recruited in Pathology Department of Inonu University, School of Medicine, Turgut Ozal Medical Center between January 2002 and December 2005. They had already undergone surgery following the preliminary diagnosis of CE and were diagnosed definitively after histopathological analysis. Thirty-seven of them were female (41%) and the rest were male (n=54, 59%). Mean age was 36.24 ± 20.35 (range: 4-80 years). Lung and liver were the most common localizations for CE cysts (n=67, 73.63%). Fifty patients' preoperative serological analysis (IHA) were already available (55%) and 46 of them (92%) were positive. Since histopathological definitive diagnosis was CE, false negative result rate was assessed as 8%. Intraabdominal CE cyst localization was found related with bigger cyst size and multiple organ involvement. Symptom duration was correlated with cyst size (p < 0.05; r < sup > 2 < /sup > =0.09). IHA results were failed to be found related with clinical features of the cysts.

摘要

囊型包虫病(CE)是由细粒棘球绦虫的幼虫形式引起的一种人畜共患感染。在本研究中,根据91例CE患者的性别、年龄、症状、囊肿定位和大小以及术前血清学分析结果进行了分析。这些患者于2002年1月至2005年12月期间在伊诺努大学医学院图尔古特·奥扎尔医学中心病理科就诊。他们在初步诊断为CE后已经接受了手术,并在组织病理学分析后得到确诊。其中37例为女性(41%),其余为男性(n = 54,59%)。平均年龄为36.24±20.35岁(范围:4 - 80岁)。肺和肝是CE囊肿最常见的发病部位(n = 67,73.63%)。50例患者(55%)有术前血清学分析(IHA)结果,其中46例(92%)呈阳性。由于组织病理学确诊为CE,假阴性结果率评估为8%。发现腹腔内CE囊肿定位与较大的囊肿大小和多器官受累有关。症状持续时间与囊肿大小相关(p < 0.05;r² = 0.09)。未发现IHA结果与囊肿的临床特征有关。

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