接受透析肾替代治疗的癫痫患者的意外猝死：一家机构17年的经验

Sudden unexpected death in patients with epilepsy receiving renal replacement therapy with dialysis: a 17-year experience at a single institution.

作者信息

Scorza Fulvio A, Scattolini Marcello, Cysneiros Roberta M, Arida Ricardo M, De Albuquerque Marly, Terra Vera C, Machado Hélio R, Gomes Rui A, Kesrouani Silvana, Cruz Jenner, Pelarigo Fátima C M, Silva Alexandre L, Henriques Tânia M G, Cavalheiro Esper A

机构信息

Disciplina de Neurologia Experimental, Universidade Federal de São Paulo/Escola Paulista de Medicina, São Paulo, SP, Brazil.

出版信息

Hemodial Int. 2010 Oct;14(4):364-9. doi: 10.1111/j.1542-4758.2010.00492.x.

DOI:10.1111/j.1542-4758.2010.00492.x

PMID:20955271

Abstract

Epilepsy is the most common acquired chronic neurological disorder; each year about 1 in a 1000 patients with chronic epilepsy die suddenly, unexpectedly, and without explanation, even with postmortem examination (SUDEP). Seizure incidence is approximately 10% in patients with chronic renal failure and hemodialysis-associated seizure has been considered to be a common complication of people on hemodialysis treatment. Considering this, we evaluated the incidence of seizures in 189 patients under dialytic treatment.

摘要

癫痫是最常见的后天性慢性神经系统疾病；每年约每1000例慢性癫痫患者中就有1例突然、意外且无明显原因地死亡，即便进行尸检也无法解释（即癫痫性猝死）。慢性肾衰竭患者的癫痫发作发生率约为10%，而血液透析相关癫痫发作一直被认为是接受血液透析治疗患者的常见并发症。考虑到这一点，我们评估了189例接受透析治疗患者的癫痫发作发生率。