Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.
Clin Exp Ophthalmol. 2011 Mar;39(2):175-7. doi: 10.1111/j.1442-9071.2010.02404.x. Epub 2010 Oct 19.
The authors report a rare case of extranodal Rosai-Dorfman disease without systemic involvement. A 14-year-old girl presented with a slowly progressive, non-tender, well-circumscribed, perilimbal nodule in the right eye. Excisional biopsy was performed and histopathologic and immunohistochemical analysis established the diagnosis. Systemic evaluation revealed no other masses. After complete excision of the epibulbar lesion, the patient is asymptomatic and remains on regular follow up with no signs of recurrence. Rosai-Dorfman disease is an infrequent, benign histiocytic disorder that can rarely manifest as an exclusive extranodal mass. We report a case of solitary epibulbar Rosai-Dorfman disease, successfully treated with complete surgical excision of the lesion.
作者报告了一例罕见的无全身受累的结外罗道尔夫病。一名 14 岁女孩右眼出现缓慢进展、无触痛、边界清楚的角膜缘周围小结节。行切除活检，组织病理学和免疫组化分析确立了诊断。全身评估未发现其他肿块。眶周病变完全切除后，患者无症状，定期随访，无复发迹象。罗道尔夫病是一种罕见的良性组织细胞疾病，偶尔表现为单一的结外肿块。我们报告一例孤立性球结膜罗道尔夫病，通过病变完全手术切除成功治疗。
