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前尿道狭窄:当前外科治疗的简要综述

Anterior urethral strictures: a brief review of the current surgical treatment.

作者信息

Singh Onkar, Gupta Shilpi Singh, Arvind Nand Kishore

机构信息

Department of Urology, Bhopal Memorial Hospital and Research Centre, Bhopal, India.

出版信息

Urol Int. 2011;86(1):1-10. doi: 10.1159/000319501. Epub 2010 Oct 19.

Abstract

A review of the recent literature on the surgical management of anterior urethral stricture was performed. The literature was searched via PubMed using the search terms 'urethral stricture' and 'urethroplasty' from 1996 to 2009. The management of anterior urethral strictures is changing rapidly in the sense that the reconstructive procedures have evolved greatly. Penile skin, because of its location and because it is hairless, has been popular and used for a long time. Since the early 1990s, buccal mucosa graft (BMG) was introduced in urethral reconstructive surgery and has become the first choice of most practicing urologists. Recently, there has been an increase in the use of lingual mucosa graft with various doctors reporting easy harvesting and lesser morbidity in comparison to BMG. Also, fibrin glue has recently been used to fix the graft with promising results. With the success of tissue-engineered materials that are still in the experimental phase, the urologist would no longer be limited by the quantity of the graft. These substitutes will also boost the appealing scarless endoscopic urethroplasty. This article provides a brief up-to-date review of the main surgical techniques in the management of anterior urethral stricture disease for the contemporary practicing urologists. Present controversies have been given special emphasis. The possible future techniques and the future of the anterior urethral stricture surgery are also discussed in brief.

摘要

对近期关于前尿道狭窄外科治疗的文献进行了综述。通过PubMed检索1996年至2009年期间使用搜索词“尿道狭窄”和“尿道成形术”的文献。前尿道狭窄的治疗正在迅速变化,因为重建手术已经有了很大的发展。阴茎皮肤因其位置和无毛的特点,长期以来一直很受欢迎并被使用。自20世纪90年代初以来,颊黏膜移植(BMG)被引入尿道重建手术,并已成为大多数执业泌尿科医生的首选。最近,舌黏膜移植的使用有所增加,各种医生报告称与BMG相比,其采集容易且发病率较低。此外,纤维蛋白胶最近已被用于固定移植组织,效果良好。随着仍处于实验阶段的组织工程材料的成功,泌尿科医生将不再受移植组织数量的限制。这些替代物也将推动有吸引力的无瘢痕内镜尿道成形术的发展。本文为当代执业泌尿科医生提供了关于前尿道狭窄疾病主要外科技术的简要最新综述。特别强调了当前的争议。还简要讨论了可能的未来技术以及前尿道狭窄手术的未来。

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