Department of Global Health and Development, LSHTM, 15-17 Tavistock Place, London, UK.
BMC Public Health. 2010 Oct 19;10:624. doi: 10.1186/1471-2458-10-624.
Neonatal mortality because of low birth weight or prematurity remains high in many developing country settings. This research aimed to estimate the sensitivity and specificity, and the positive and negative predictive values of newborn foot length to identify babies who are low birth weight or premature and in need of extra care in a rural African setting.
A cross-sectional study of newborn babies in hospital, with community follow-up on the fifth day of life, was carried out between 13 July and 16 October 2009 in southern Tanzania. Foot length, birth weight and gestational age were estimated on the first day and foot length remeasured on the fifth day of life.
In hospital 529 babies were recruited and measured within 24 hours of birth, 183 of whom were also followed-up at home on the fifth day. Day one foot length <7 cm at birth was 75% sensitive (95%CI 36-100) and 99% specific (95%CI 97-99) to identify very small babies (birth weight <1500 grams); foot length <8 cm had sensitivity and specificity of 87% (95%CI 79-94) and 60% (95%CI 55-64) to identify those with low birth weight (<2500 grams), and 93% (95%CI 82-99) and 58% (95%CI 53-62) to identify those born premature (<37 weeks). Mean foot length on the first day was 7.8 cm (standard deviation 0.47); the mean difference between first and fifth day foot lengths was 0.1 cm (standard deviation 0.3): foot length measured on or before the fifth day of life identified more than three-quarters of babies who were born low birth weight.
Measurement of newborn foot length for home births in resource poor settings has the potential to be used by birth attendants, community volunteers or parents as a screening tool to identify low birth weight or premature newborns in order that they can receive targeted interventions for improved survival.
在许多发展中国家,由于低出生体重或早产导致的新生儿死亡率仍然很高。本研究旨在评估新生儿足部长度来识别低出生体重或早产并需要额外护理的婴儿的敏感性和特异性,以及阳性和阴性预测值,该研究在非洲农村地区进行。
这是一项 2009 年 7 月 13 日至 10 月 16 日在坦桑尼亚南部进行的医院内新生儿的横断面研究,在生命的第五天进行社区随访。在出生后的第一天估计足部长度、出生体重和胎龄,并在第五天再次测量足部长度。
在医院内共招募并测量了 529 名出生后 24 小时内的婴儿,其中 183 名婴儿还在第五天进行了家庭随访。出生时第一天的足部长度<7cm 对识别非常小的婴儿(出生体重<1500 克)有 75%的敏感性(95%CI 36-100)和 99%的特异性(95%CI 97-99);足部长度<8cm 对识别出生体重低(<2500 克)的婴儿的敏感性和特异性分别为 87%(95%CI 79-94)和 60%(95%CI 55-64),对识别早产(<37 周)的婴儿的敏感性和特异性分别为 93%(95%CI 82-99)和 58%(95%CI 53-62)。第一天的平均足部长度为 7.8cm(标准差 0.47);第一天和第五天的足部长度平均差异为 0.1cm(标准差 0.3):出生后第五天内测量的足部长度可以识别出超过四分之三的低出生体重婴儿。
在资源匮乏的环境中,为家庭分娩的新生儿测量足部长度,有可能被分娩助手、社区志愿者或父母用作筛查工具,以识别低出生体重或早产新生儿,以便他们能够接受有针对性的干预措施以提高生存率。