Baqui Abdullah H, Ahmed Saifuddin, El Arifeen Shams, Darmstadt Gary L, Rosecrans Amanda M, Mannan Ishtiaq, Rahman Syed M, Begum Nazma, Mahmud Arif B A, Seraji Habibur R, Williams Emma K, Winch Peter J, Santosham Mathuram, Black Robert E
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
BMJ. 2009 Aug 14;339:b2826. doi: 10.1136/bmj.b2826.
To assess the effect of the timing of first postnatal home visit by community health workers on neonatal mortality.
Analysis of prospectively collected data using time varying discrete hazard models to estimate hazard ratios for neonatal mortality according to day of first postnatal home visit.
Data from a community based trial of neonatal care interventions conducted in Bangladesh during 2004-5.
Neonatal mortality.
9211 live births were included. Among infants who survived the first day of life, neonatal mortality was 67% lower in those who received a visit on day one than in those who received no visit (adjusted hazard ratio 0.33, 95% confidence interval 0.23 to 0.46; P<0.001). For those infants who survived the first two days of life, receiving the first visit on the second day was associated with a 64% lower neonatal mortality than in those who did not receive a visit (adjusted hazard ratio 0.36, 0.23 to 0.55; P<0.001). First visits on any day after the second day of life were not associated with reduced mortality.
In developing countries, especially where home delivery with unskilled attendants is common, postnatal home visits within the first two days of life by trained community health workers can significantly reduce neonatal mortality.
评估社区卫生工作者首次产后家访时间对新生儿死亡率的影响。
使用时变离散风险模型对前瞻性收集的数据进行分析,以根据首次产后家访日期估计新生儿死亡率的风险比。
2004 - 2005年在孟加拉国进行的一项基于社区的新生儿护理干预试验的数据。
新生儿死亡率。
纳入9211例活产儿。在生命第一天存活的婴儿中,第一天接受家访的婴儿的新生儿死亡率比未接受家访的婴儿低67%(调整后的风险比为0.33,95%置信区间为0.23至0.46;P<0.001)。对于那些生命前两天存活的婴儿,第二天接受首次家访的婴儿的新生儿死亡率比未接受家访的婴儿低64%(调整后的风险比为0.36,0.23至0.55;P<0.001)。生命第二天之后的任何一天进行首次家访与死亡率降低无关。
在发展中国家,尤其是在家中由无技能人员接生很常见的地方,训练有素的社区卫生工作者在生命的前两天进行产后家访可显著降低新生儿死亡率。