Department of Animal Science, Faculty of Agriculture, University of Guilan, P.O. Box 41635-1314, Rasht, Iran.
C R Biol. 2010 Oct;333(10):710-5. doi: 10.1016/j.crvi.2010.07.001. Epub 2010 Aug 23.
Stochastic modeling of dairy cattle populations using multiple ovulation and embryo transfer (MOET) was used to compare 15-year genetic responses with an artificial insemination (AI) program. MOET and AI techniques were simulated in four populations, two with 100 breeding females each and two with 400 breeding females. The selection goal was to maximize genetic progress in milk yield. The reduction in genetic variation due to inbreeding and linkage disequilibrium was accounted for in the simulation process. All four MOET breeding schemes studied achieved larger genetic responses than the realized and theoretical genetic gains from the current AI progeny testing populations. Strict restriction against inbred matings slowed genetic progress significantly in the small population but would not be consequential in the larger population. However, allowing inbred matings in the smaller population caused a rapid accumulation of inbreeding. Linkage disequilibrium was as important as inbreeding in reducing genetic variation. Genetic drift variance was much smaller in the larger population.
使用多次排卵和胚胎移植(MOET)对奶牛群体进行随机建模,以比较 15 年的遗传反应与人工授精(AI)计划。MOET 和 AI 技术在四个群体中进行了模拟,其中两个群体各有 100 头繁殖母牛,两个群体各有 400 头繁殖母牛。选择目标是最大限度地提高产奶量的遗传进展。在模拟过程中考虑了由于近亲繁殖和连锁不平衡导致的遗传变异减少。所有四个研究的 MOET 繁殖计划都实现了比当前 AI 后代测试群体更大的遗传反应。在小群体中严格限制近亲交配会显著减缓遗传进展,但在更大的群体中不会产生影响。然而,允许小群体中的近亲交配会导致近亲繁殖的迅速积累。连锁不平衡与近亲繁殖一样重要,会降低遗传变异。在较大的群体中,遗传漂移方差要小得多。