Cleveland Clinic, Cleveland, Ohio 44195, USA.
JACC Cardiovasc Interv. 2010 Oct;3(10):995-1000. doi: 10.1016/j.jcin.2010.08.012.
Clopidogrel pharmacogenomics has received significant attention since a black box warning was announced by the Food and Drug Administration in March. This has left clinicians in a difficult situation where many questions remain unanswered. In this brief viewpoint article, we ask some pointed questions of our own and outline the pathway that needs to be taken for clinical translation to occur.
氯吡格雷药物基因组学自 3 月美国食品和药物管理局发布黑框警告以来,受到了广泛关注。这使得临床医生陷入了困境,许多问题仍未得到解答。在这篇简短的观点文章中,我们提出了一些尖锐的问题,并概述了实现临床转化所需的途径。