Chen Hong-wu, Huang Wei-ming
Department of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2010 Oct;30(10):2396-8.
To study the effect of automated peripheral arteriovenous exchange transfusion for treatment of severe hyperbilirubinemia in neonates.
Fifty-three neonates with severe hyperbilirubinemia underwent automated peripheral arteriovenous exchange transfusion, and the changes in the blood gas, electrolytes and some biochemical indices after the exchange transfusion were evaluated.
Treatment with the exchange transfusion resulted in a significant reduction in the total serum bilirubin with an exchange rate of 53.12% (P<0.01). The levels of serum kalium, calcium, magnesium, white blood cell count, platelets, and pH showed reductions while blood glucose exhibited a significant elevation changes after the transfusion (P<0.01), which all recovered the normal levels within 48 h. No obvious alterations occurred in the respiration, heart rate, blood pressure, or saturation of blood oxygen during the transfusion.
Automated peripheral arteriovenous exchange transfusion can rapidly reduce serum bilirubin levels in neonates with severe hyperbilirubinemia without obviously affecting the blood gas balance or blood electrolyte or glucose levels.
研究自动外周动静脉换血疗法治疗新生儿重度高胆红素血症的效果。
53例重度高胆红素血症新生儿接受自动外周动静脉换血治疗，评估换血后血气、电解质及一些生化指标的变化。
换血治疗使血清总胆红素显著降低，换血率为53.12%（P<0.01）。输血后血清钾、钙、镁、白细胞计数、血小板及pH值降低，而血糖显著升高（P<0.01），均在48小时内恢复至正常水平。输血过程中呼吸、心率、血压或血氧饱和度无明显改变。
自动外周动静脉换血疗法可迅速降低重度高胆红素血症新生儿的血清胆红素水平，且不明显影响血气平衡、血液电解质或血糖水平。
