冠状动脉疾病中的心肌氧供应

Myocardial oxygen supply in coronary artery disease.

作者信息

Thomas M, Grote J, Nitsch J

机构信息

Department of Physiology, University of Bonn, FRG.

出版信息

Adv Exp Med Biol. 1990;277:483-7. doi: 10.1007/978-1-4684-8181-5_54.

DOI:10.1007/978-1-4684-8181-5_54

PMID:2096652

Abstract

In patients with coronary artery disease investigated during cardiac catheterisation, myocardial blood flow and myocardial oxygen consumption were significantly decreased as compared to control patients without signs of coronary artery disease. At the same time left ventricular function was impaired. In addition to regional contraction abnormalities observed in 77% of the patients, mean heart index and mean left ventricular work were diminished and mean enddiastolic pressure elevated. Among the coronary artery disease group, patients with normal blood pressure had a significantly higher left ventricular enddiastolic pressure than patients with hypertension.

摘要

在接受心导管检查的冠心病患者中，与无冠心病迹象的对照患者相比，心肌血流量和心肌耗氧量显著降低。同时，左心室功能受损。除77%的患者观察到局部收缩异常外，平均心脏指数和平均左心室作功降低，平均舒张末期压力升高。在冠心病组中，血压正常的患者左心室舒张末期压力显著高于高血压患者。