大鼠和仓鼠发情周期中子宫内氧张力的变化及其受卵巢甾体激素的调节：一项比较研究。

Alterations in intrauterine oxygen tension during the estrous cycle in the rat and hamster and its regulation by ovarian steroid hormones: a comparative study.

作者信息

Kaufman D L, Mitchell J A

机构信息

Department of Anatomy/Cell Biology, Wayne State University School of Medicine, Detroit, Michigan.

出版信息

Adv Exp Med Biol. 1990;277:745-50. doi: 10.1007/978-1-4684-8181-5_85.

DOI:10.1007/978-1-4684-8181-5_85

PMID:2096675

Abstract

The results indicate that marked fluctuations in oxygen availability occur during the estrous cycle in both rats and hamsters. Patterns of luminal pO2 were similar in that levels were intermediate during metestrus and maximal during diestrus. By contrast, minimal pO2 levels occurred during estrus in the rat vs. during proestrus in the hamster. The species also differed in the range of mean pO2 occurring during the cycle: approximately 5-50 mmHg in the hamster vs. 25-50 mmHg in the rat. Ovariectomy results in marked increases in luminal pO2 in both species. The increase is reduced by hormone replacement.

摘要

结果表明，大鼠和仓鼠在发情周期中氧供应均出现显著波动。管腔 pO2 的模式相似，即在间情期水平处于中等，在动情后期达到最高。相比之下，大鼠在发情期时 pO2 水平最低，而仓鼠在发情前期时 pO2 水平最低。这两个物种在发情周期中平均 pO2 的范围也有所不同：仓鼠约为 5 - 50 mmHg，大鼠为 25 - 50 mmHg。卵巢切除术导致两个物种的管腔 pO2 显著升高。激素替代可减轻这种升高。