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Probing the mechanism of pancreatic phospholipase A2 with the aid of recombinant DNA techniques.

作者信息

Kuipers O P, van den Bergh C J, Verheij H M, de Haas G H

机构信息

Department of Biochemistry, State University of Utrecht, CBLE, University Center De Uithof, The Netherlands.

出版信息

Adv Exp Med Biol. 1990;279:65-84. doi: 10.1007/978-1-4613-0651-1_5.

DOI:10.1007/978-1-4613-0651-1_5
PMID:2096701
Abstract
摘要

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Identification of a specific region of low molecular weight phospholipases A2 (residues 21-40) as a potential target for structure-based design of inhibitors of these enzymes.鉴定低分子量磷脂酶A2的一个特定区域（第21-40位氨基酸残基）作为基于结构设计这些酶抑制剂的潜在靶点。
Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10290-4. doi: 10.1073/pnas.90.21.10290.