Selection of treatment for muscle infiltrating transitional cell bladder cancer.

1. Cancers of the bladder are heterogeneous. 2. A variety of surgical and radiation treatments has been useful in local tumor control. 3. Rational selection for optimal local therapy requires definition of more specific selection criteria. 4. The favorable effects of chemotherapy in patients with advanced bladder cancer warrant clinical investigation of such treatment in adjuvant and neoadjuvant settings while the search for more effective chemotherapy continues.