Neĭmark A I, Riapolova M V, Mel'nik M A
Urologiia. 2010 Mar-Apr(2):36-8.
The clinic at the nephrology and urology chair of the State Altai Medical University admitted 40 females aged 20-74 years with overactive bladder (OAB) symptoms and imperative urinary incontinence (IUI) in 2008-2009. The patients were divided into two groups: 20 patients of group 1 received an anticholinesterase drug solifenacin (vesikar) in a dose 5 mg/day; 20 patients of group 2 received combined treatment. The course of treatment lasted for 1-3 months. As shown by the voiding diary and uroflowmetry, vesikar noticeably reduced or eliminated the rate and intensity of imperative voiding. Urodynamic parameters also changed positively. The treatment prolonged voiding time and volume, lowered Qmax. The effect was persistent.
2008年至2009年期间，阿尔泰国立医科大学肾病与泌尿学系诊所收治了40名年龄在20至74岁之间、有膀胱过度活动症（OAB）症状和急迫性尿失禁（IUI）的女性患者。患者被分为两组：第一组20名患者接受剂量为5毫克/天的抗胆碱酯酶药物索利那新（卫喜康）治疗；第二组20名患者接受联合治疗。治疗疗程持续1至3个月。排尿日记和尿流率测定结果显示，卫喜康显著降低或消除了急迫排尿的频率和强度。尿动力学参数也出现了积极变化。治疗延长了排尿时间和尿量，降低了最大尿流率（Qmax）。疗效持久。
