乳腺纤维瘤样化生癌作为细针穿刺细胞学检查的诊断陷阱：一例报告

Fibromatosislike metaplastic carcinoma of the breast as a diagnostic pitfall for fine needle aspiration cytology: a case report.

作者信息

Jarboe Elke, Layfield Lester J, Collins Brian

机构信息

Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA.

出版信息

Acta Cytol. 2010 Sep-Oct;54(5):712-6. doi: 10.1159/000325238.

DOI:10.1159/000325238

PMID:20968161

Abstract

UNLABELLED

BACKGROUND Metaplastic carcinomas of the breast are uncommon, and most display marked cellular atypia. Recently, a low grade fibromatosis-like metaplastic carcinoma was found and displayed little nuclear atypia. CASE A 74-year-old woman presented with a 2.5-cm, palpable breast nodule. Mammogram was reported as suspicious for malignancy. Cytologic examination revealed smears of low cellularity with most cells lying in clusters and having a round or oval shape. Rare cells had a "spindle" shape. Nuclear features were low grade. Rare individual cells had retained cytoplasm. Lumpectomy revealed a fibromatosis-like metaplastic carcinoma.

CONCLUSION

Cytologically, fibromatosis-like metaplastic carcinomas are low grade lesions producing smears of relatively low cellularity. Separation from ductal carcinomas is necessary because fibromatosis-like metaplastic carcinomas rarely metastasize to lymph nodes.

摘要

未标注

背景乳腺化生性癌并不常见，且大多数表现出明显的细胞异型性。最近，发现了一种低级别纤维瘤病样化生性癌，其核异型性较小。病例一名74岁女性，乳房可触及一个2.5厘米的结节。乳腺钼靶检查报告怀疑为恶性。细胞学检查显示涂片细胞数量少，大多数细胞呈簇状，圆形或椭圆形。罕见细胞呈“纺锤形”。核特征为低级别。罕见的单个细胞保留了细胞质。肿块切除术显示为纤维瘤病样化生性癌。