South China Normal University, Guangzhou 510631, China.
Neurosci Lett. 2011 Jan 7;487(2):234-9. doi: 10.1016/j.neulet.2010.10.029. Epub 2010 Oct 20.
Nucleus robust arcopallium (RA) of the songbird is a distinct forebrain region that is essential for song production. To explore the electrophysiological properties, whole cell recordings were made from adult zebra finch RA neurons in slice preparations. Based on the electrophysiological properties, neurons in RA were classified into two distinct classes. Type I neurons were spontaneously active. They had larger input resistance, longer time constant, larger time-peak of an afterhyperpolarization (AHP), and broader action potentials than those of the other class. A slow, time-dependent inward rectification was induced by hyperpolarizing current pulses in this type of neuron, and was blocked by external CsCl (2mM). Type II neurons had a more negative resting membrane potential than that of type I neurons. They were characterized by a steeper slope of the recovery from the peak of the AHP and frequency-current relationships, a higher firing threshold, and irregular spiking in response to depolarizing current injection.
鸣禽的坚实弓状核（RA）是一个独特的前脑区域，对于歌曲的产生至关重要。为了探究其电生理特性，我们在切片标本中对成年斑马雀 RA 神经元进行了全细胞膜片钳记录。根据电生理特性，RA 中的神经元被分为两种不同的类型。I 型神经元具有自发性活性。它们具有更大的输入电阻、更长的时间常数、更大的后超极化峰（AHP）时间峰值，以及比其他类型更宽的动作电位。在这种类型的神经元中，通过超极化电流脉冲诱导缓慢、依赖时间的内向整流，而这种内向整流可被外部 CsCl（2mM）阻断。II 型神经元的静息膜电位比 I 型神经元更负。它们的特征是从 AHP 峰的恢复斜率更陡，频率电流关系，更高的发射阈值，以及在对去极化电流注入的反应中不规则的放电。
