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Acute megakaryoblastic leukemia with massive myelofibrosis: complete remission and reversal of marrow fibrosis with allogeneic bone marrow transplantation as the only treatment.

作者信息

Bullorsky E O, Shanley C M, Stemmelin G, Venditti J, Lajous J R

机构信息

Department of Hematology, British Hospital of Buenos Aires, Argentina.

出版信息

Bone Marrow Transplant. 1990 Dec;6(6):449-52.

PMID:2097015
Abstract

We report results of allogeneic bone marrow transplantation in an 8-year-old boy with acute megakaryoblastic leukemia characterized by intense fibrosis together with 20% blast cells in the bone marrow, who was transplanted without preceding chemotherapy for remission induction. Conditioning comprised cytosine arabinoside, cyclophosphamide and total body irradiation. The donor was his HLA-identical sister. The patient is well with minor chronic graft-versus-host disease and normal hematologic values 670 days post-transplant.

摘要

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