Department of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada.
Laryngoscope. 2010 Dec;120(12):2452-5. doi: 10.1002/lary.21121.
OBJECTIVES/HYPOTHESIS: To describe our experience with the use of intralesional corticosteroid injection and dilatation (ILCD) in the management of subglottic stenosis (SGS).
Retrospective chart review.
A retrospective chart review was performed of all patients with SGS requiring ILCD, from 2003 to 2008, at the Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Hospital, Toronto, Canada.
Twelve patients with SGS underwent 36 ILCD operations with a mean of three procedures per patient. We identified eight patients with Wegener's granulomatosis (WG) and four patients without WG. The eight WG patients received an average of 3.37 procedures, whereas non-WG patients required an average of 2.25 procedures. This maintained airway patency and symptom control for an average of 11.9 and 8.1 months, respectively. Only one complication was identified, and no long-term sequelae were found. No patients required new tracheotomies and one patient with a previous tracheotomy was successfully decannulated.
Our data supports the use of ILCD as a safe and effective treatment of SGS in both WG and non-WG patients.
目的/假说：描述我们在治疗声门下狭窄（SGS）中使用腔内皮质类固醇注射和扩张（ILCD）的经验。
回顾性图表审查。
对 2003 年至 2008 年在加拿大多伦多西奈山医院耳鼻喉科头颈外科接受 ILCD 的所有 SGS 患者进行了回顾性图表审查。
12 名 SGS 患者接受了 36 次 ILCD 手术，平均每位患者进行了 3 次手术。我们确定了 8 名患有韦格纳肉芽肿（WG）的患者和 4 名没有 WG 的患者。8 名 WG 患者平均接受了 3.37 次手术，而非 WG 患者平均接受了 2.25 次手术。这分别维持气道通畅和症状控制的平均时间为 11.9 个月和 8.1 个月。仅发现 1 种并发症，未发现长期后遗症。没有患者需要新的气管切开术，1 名先前接受气管切开术的患者成功拔管。
我们的数据支持将 ILCD 用作 WG 和非 WG 患者 SGS 的安全有效治疗方法。
