Research Institute of Instrumentation Frontier, National Institute of Advanced Industrial Science and Technology, 1-1-1 Umezono, Tsukuba, Ibaraki 305-8568, Japan.
Rapid Commun Mass Spectrom. 2010 Nov 30;24(22):3290-6. doi: 10.1002/rcm.4780.
Mass spectrometry (MS) is a method of analyzing ions based on their mass/charge (m/z) ratios. The m/z peak identification requires speculation on the ionic unit-charge states. This problem can be solved by using superconducting junction devices to measure the kinetic energies of single molecules. However, the kinetic energy measurement is followed by the dead time of 1-20 µs, which is fatally slow for modern high-resolution time-of-flight (TOF) analyzers. In this paper, we demonstrate that a superconducting nano-stripline detector (SSLD) composed of a 10-nm-thick and 800-nm-wide NbN strip realizes the charge-state derivation, and furthermore satisfies the ideal MS detector specifications such as a nano-second response, a short recovery time, a wide mass range, and no noise.
质谱分析（MS）是一种基于离子质荷比（m/z）的分析方法。m/z 峰的识别需要推测离子的单位电荷状态。这个问题可以通过使用超导结器件来测量单个分子的动能来解决。然而，动能测量后存在 1-20μs 的死区时间，对于现代高分辨率飞行时间（TOF）分析器来说，这个时间非常慢。在本文中，我们证明了由 10nm 厚和 800nm 宽的 NbN 条组成的超导纳米线探测器（SSLD）实现了电荷状态的推导，并且满足理想的 MS 探测器规格，如纳秒级响应、短恢复时间、宽质量范围和无噪声。
