Mistry P, Chawla K P, Rai H P, Jaiswal P
Department of Medicine, Seth G. S. Medical College, Parel, Bombay, Maharashtra.
J Postgrad Med. 1990 Jan;36(1):1-4.
Plasma fibrinogen levels were estimated in 56 patients of stroke, admitted in the hospital within 24 hours of symptoms. The levels were found to be raised significantly (531.73 +/- 74 mg%) compared to those of the age and sex matched control group (445.78 +/- 92.28 mg%). When the levels in stroke group with one risk factor were compared to those of individuals with comparable control group with same risk factor, a significant difference was observed in hypertensive, smokers, alcoholics and atherosclerotic stroke groups, which indicates that the observed rise is related to phenomenon of stroke rather than the associated risk factors. However, the rise observed in hypertensive stroke group (554.26 +/- 47.08 mg%) is significantly more (p. less than 0.01) than that occurring for nonhypertensive stroke group (497.82 +/- 93.12 mg%) indicating that the presence of hypertension does contribute to the rise.
对56例脑卒中患者在出现症状后24小时内入院时的血浆纤维蛋白原水平进行了评估。与年龄和性别匹配的对照组（445.78±92.28mg%）相比，发现这些患者的血浆纤维蛋白原水平显著升高（531.73±74mg%）。当将具有一种危险因素的脑卒中组的水平与具有相同危险因素的可比对照组个体的水平进行比较时，在高血压、吸烟者、酗酒者和动脉粥样硬化性脑卒中组中观察到显著差异，这表明观察到的升高与脑卒中现象有关，而非相关危险因素。然而，高血压性脑卒中组观察到的升高（554.26±47.08mg%）明显高于非高血压性脑卒中组（497.82±93.12mg%）（p＜0.01），表明高血压的存在确实促成了这种升高。
