Perrett Conal M, Macedo Chrystalla, Francis Nicholas, Ion Lucian, Bunker Christopher B
Department of Dermatology, Chelsea and Westminster NHS Foundation Trust, London, UK.
J Cutan Pathol. 2011 Apr;38(4):357-9. doi: 10.1111/j.1600-0560.2010.01642.x. Epub 2010 Oct 26.
Atypical fibroxanthoma is a neoplasm primarily occurring in older patients, with a predilection for photo-damaged skin of the head and neck. Compared to the immunocompetent population, patients infected with HIV have a higher risk of certain malignancies including non-Hodgkin lymphoma, Kaposi's sarcoma and skin cancer. Although atypical fibroxanthoma has been reported in another immunocompromised group, namely organ transplant recipients, there are no previous reports in the published literature of this tumour arising in patients infected with HIV. We report a case of an atypical fibroxanthoma arising in a 71- year old HIV-positive male.
非典型纤维黄色瘤是一种主要发生于老年患者的肿瘤,好发于头颈部受光损伤的皮肤。与免疫功能正常人群相比,感染HIV的患者患某些恶性肿瘤的风险更高,包括非霍奇金淋巴瘤、卡波西肉瘤和皮肤癌。虽然在另一免疫功能低下群体即器官移植受者中曾有非典型纤维黄色瘤的报道,但在已发表的文献中尚无HIV感染患者发生该肿瘤的先例。我们报告一例71岁HIV阳性男性发生非典型纤维黄色瘤的病例。