Rahman Zillur, Hannan Jafrul, Islam Saiful
Department of Pathology, Chittagong Medical College, Chittagong, Bangladesh.
J Indian Assoc Pediatr Surg. 2010 Apr;15(2):56-8. doi: 10.4103/0971-9261.70640.
The diagnosis of Hirschsprung's disease (HD) is dependent on the histological study of rectal ganglion cells, and an open rectal biopsy was the mainstay that required general anaesthesia (GA) and carried risk of postoperative rectal bleeding. Suction rectal biopsy later gained wide acceptance and became the choice as there is no requirement of GA and virtual absence of any complications.
A retrospective review of the histological findings of 216 rectal suction biopsies studied from 2005 to 2009.
There were 143 male and 73 female children. 196 (90.7%) children were within 1 year of age. Among 216 rectal suction biopsies 181 (83.80%) were aganglionic, 27 (12.5%) were ganglionic and 8 (3.7%) were inadequate. Majority of patients were of less than 1 year of age (94.47%).
The rectal suction biopsy is a bed side procedure, safe, cheap and time saving. There is high degree of accuracy, simplicity and absence of complications.
先天性巨结肠（HD）的诊断依赖于直肠神经节细胞的组织学研究，开放式直肠活检是主要方法，但需要全身麻醉（GA），且有术后直肠出血的风险。后来，吸引式直肠活检得到广泛认可并成为首选，因为它不需要全身麻醉，而且几乎没有任何并发症。
对2005年至2009年期间研究的216例直肠吸引活检的组织学结果进行回顾性分析。
有143名男童和73名女童。196名（90.7%）儿童年龄在1岁以内。在216例直肠吸引活检中，181例（83.80%）无神经节，27例（12.5%）有神经节，8例（3.7%）样本不足。大多数患者年龄小于1岁（94.47%）。
直肠吸引活检是一种床边操作，安全、廉价且省时。具有高度的准确性、简便性且无并发症。
