CareFusion, Middleton, Wisconsin, USA.
Muscle Nerve. 2010 Nov;42(5):798-807. doi: 10.1002/mus.21824.
The motor unit number index (MUNIX) is a method for assessment of number and size (MUSIX) of motor units (MUs) using the compound muscle action potential (CMAP) and surface electromyographic interference pattern (SIP). This method was used to study the hypothenar muscle in 34 healthy subjects to define normal range, and to study reproducibility. Four healthy subjects and 13 patients with amyotrophic lateral sclerosis (ALS) were studied serially over a 1-year period. In healthy subjects, MUNIX showed good reproducibility. In serial studies, healthy subjects showed no change in the CMAP amplitude and MUNIX. ALS patients with minimal change in CMAP amplitude had a significant drop in MUNIX and increase in MUSIX, indicating MU loss compensated by reinnervation. When the CMAP changed significantly (>30%) in 1 year, the CMAP and MUNIX decreased in parallel. MUNIX would be useful to study MU loss in degenerative diseases of motor neurons. Muscle Nerve 42: 798-807, 2010.
运动单位数量指数（MUNIX）是一种使用复合肌肉动作电位（CMAP）和表面肌电图干扰图案（SIP）评估运动单位（MU）数量和大小（MUSIX）的方法。该方法用于研究 34 名健康受试者的小鱼际肌，以定义正常范围，并研究其可重复性。对 4 名健康受试者和 13 名肌萎缩侧索硬化症（ALS）患者进行了为期 1 年的连续研究。在健康受试者中，MUNIX 具有良好的可重复性。在连续研究中，健康受试者的 CMAP 幅度和 MUNIX 没有变化。CMAP 幅度变化最小的 ALS 患者的 MUNIX 明显下降，MUSIX 增加，表明 MU 丢失得到了再支配的补偿。当 CMAP 在 1 年内显著变化（>30%）时，CMAP 和 MUNIX 平行下降。MUNIX 可用于研究运动神经元退行性疾病中的 MU 丢失。《肌肉神经》42：798-807，2010 年。
