Department of Neurology, The University of Kansas Medical Center, Kansas City, Kansas, USA.
Muscle Nerve. 2010 Nov;42(5):833-5. doi: 10.1002/mus.21849.
Creutzfeldt-Jakob disease (CJD) is a degenerative neurological disorder caused by a prion protein. The diagnosis may be challenging in unusual early presentations. A bulbar symptom as the initial complaint is a rare presentation for CJD, with only a few reports so far. These patients can be misdiagnosed with motor neuron disease or the Miller Fisher variant of Guillain-Barré syndrome. We describe a 69-year-old woman with CJD who presented with bulbar symptoms at the onset.
克雅氏病（CJD）是一种由朊病毒蛋白引起的退行性神经疾病。在不常见的早期表现中，诊断可能具有挑战性。球部症状作为首发症状是 CJD 的罕见表现，迄今为止仅有少数报道。这些患者可能被误诊为运动神经元病或格林-巴利综合征的米勒-费舍尔变异型。我们描述了一位 69 岁女性，她以球部症状起病，患有 CJD。
