The Medical University of Warsaw, Department of Internal Medicine, Hypertension and Vascular Diseases, 1a Banacha Street, 02-097 Warsaw, Poland.
Expert Opin Pharmacother. 2010 Nov;11(16):2579-97. doi: 10.1517/14656566.2010.513972.
Despite extensive clinical research, still there is some uncertainty regarding management of hypertension, in particular initial and goal blood pressure levels and selection of optimal pharmacotherapy, as well as concomitant medications, to reduce other risk factors.
An overview of recent findings from major clinical trials in hypertension (until July 2010), along with a reappraisal of the European Society of Hypertension 2009 guidelines.
Practical overview of the management of hypertension, including threshold and goal blood pressure in specific situations, choice of antihypertensive medications and indications for treatment of concomitant risk factors.
Primary benefits of antihypertensive therapy are mediated by blood pressure reduction and the majority of patients will require at least two drugs, with the preference of fixed-dose combinations for effective blood pressure control.
尽管有广泛的临床研究，仍然有一些不确定性的管理高血压，特别是初始和目标血压水平和选择最佳的药物治疗，以及伴随的药物，以减少其他危险因素。
概述了最近的发现主要临床试验中的高血压（截至 2010 年 7 月），以及重新评估欧洲高血压学会 2009 年的指南。
实用的管理高血压，包括阈值和目标血压在特定情况下，选择抗高血压药物和治疗的适应症同时发生的危险因素。
抗高血压治疗的主要好处是通过降低血压和大多数患者将需要至少两种药物，与固定剂量的组合有效控制血压的偏好。
