Sunderić Dj, Dozić S, Hosovski E
Health Centre, Titovo Uzice.
Srp Arh Celok Lek. 1990 Jul-Aug;118(7-8):261-4.
The results of histochemical and histopathologic tests of a periphery nerve in rats which were chronically poisoned with copper, are presented. The tests were performed on 45 albino Wistar female rats, which were poisoned with pure copper powder in an inhalation chamber for one year. The control group consisted of 16 rats. By histochemical test the copper pigment was found in 46.66% of the poisoned rats. It was located in epineurium and perineurium, cells and less in the endoneurium. It was also found in cells of the blood vessel media of a periphery nerve. Histopathological changes in a periphery nerve were discrete and they appeared in the form of certain swollen axones.
本文呈现了长期铜中毒大鼠外周神经的组织化学和组织病理学检测结果。实验选取了45只白化Wistar雌性大鼠，在吸入式实验舱中用纯铜粉使其中毒一年。对照组由16只大鼠组成。通过组织化学检测发现，46.66%的中毒大鼠体内存在铜色素。其位于神经外膜和神经束膜，细胞中也有发现，在神经内膜中较少。在周围神经的血管中层细胞中也发现了铜色素。周围神经的组织病理学变化不明显，表现为某些轴突肿胀。
