FGF 信号通路：在早期脊椎动物胚胎发生中的多种作用。
FGF signalling: diverse roles during early vertebrate embryogenesis.
机构信息
The Healing Foundation Centre, Michael Smith Building, Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
出版信息
Development. 2010 Nov;137(22):3731-42. doi: 10.1242/dev.037689.
Abstract
Fibroblast growth factor (FGF) signalling has been implicated during several phases of early embryogenesis, including the patterning of the embryonic axes, the induction and/or maintenance of several cell lineages and the coordination of morphogenetic movements. Here, we summarise our current understanding of the regulation and roles of FGF signalling during early vertebrate development.
摘要
成纤维细胞生长因子 (FGF) 信号在胚胎发生的几个阶段中都有涉及，包括胚胎轴的模式形成、几个细胞谱系的诱导和/或维持以及形态发生运动的协调。在这里，我们总结了我们目前对早期脊椎动物发育过程中 FGF 信号的调节和作用的理解。
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