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[卒中诊所对他汀类药物用于缺血性卒中二级预防的影响]

[Impacts of stroke clinics on the utilization of statins for secondary prevention of ischemic stroke].

作者信息

Shao Bei-li, Geng Jie-li, Li Yan-sheng

机构信息

Department of Neurology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.

出版信息

Zhonghua Nei Ke Za Zhi. 2010 Jul;49(7):595-8.

PMID:20979771
Abstract

OBJECTIVE

To describe the impact of stroke clinic on the usage of statins for secondary prevention of ischemic stroke.

METHODS

Data about the demography, social economic status, personal histories, blood lipid profiles, and the status of the usage of statins from 568 serial ischemic stroke patients were retrospectively analysed.

RESULTS

A total of 51.3% patients followed up in stroke clinic (306 patients) and 7.6% patients followed up in general clinic (262 patients) were treated with statins. 71.6% patients with and 44.8% patients without hyperlipidemia in stroke clinics were taking statins, which were higher than that patients in the general clinics (27.1% and 2.0% respectively). The patients in the stroke clinics with high LDL-C level (>3.4 mmol/L) were more likely to be treated with statins than those with lower level (25.6% vs 14.7%, P=0.017).

CONCLUSIONS

The rate of statins usage is extremely low in stroke patients followed up in a general clinic, but it can been improved greatly in a stroke clinic. Stroke clinic can narrow the gap between the clinical practice and the guideline for secondary prevention of ischemic stroke.

摘要

目的

描述卒中门诊对他汀类药物用于缺血性卒中二级预防的影响。

方法

回顾性分析568例连续性缺血性卒中患者的人口统计学、社会经济状况、个人史、血脂谱及他汀类药物使用情况。

结果

在卒中门诊随访的患者中有51.3%(306例)接受了他汀类药物治疗,在普通门诊随访的患者中有7.6%(262例)接受了他汀类药物治疗。卒中门诊中血脂异常患者和无血脂异常患者使用他汀类药物的比例分别为71.6%和44.8%,高于普通门诊患者(分别为27.1%和2.0%)。卒中门诊中低密度脂蛋白胆固醇(LDL-C)水平高(>3.4 mmol/L)的患者比水平低的患者更有可能接受他汀类药物治疗(25.6%对14.7%,P=0.017)。

结论

在普通门诊随访的卒中患者中他汀类药物使用率极低,但在卒中门诊中可大幅提高。卒中门诊可缩小缺血性卒中二级预防临床实践与指南之间的差距。

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