Mirabile Lorenzo, Serio P Paola, Baggi R Roberto, Couloigner V Vincent
Pediatric Anesthesiology and Intensive Care Department, Azienda Ospedaliera Anna Meyer, Firenze, Italy.
Int J Pediatr Otorhinolaryngol. 2010 Dec;74(12):1409-14. doi: 10.1016/j.ijporl.2010.09.020. Epub 2010 Oct 25.
To analyze the outcome of a new endoscopic approach for the treatment of pediatric subglottic stenosis.
Case series.
Tertiary care center.
Eighteen pediatric cases of grade II to IV subglottic stenosis (8 congenital and 10 acquired) consecutively treated at our institutions by Endoscopic Anterior Cricoid Split (EACS) and balloon dilation between 2006 and 2010. Treatment protocol encompassed systematic postoperative laryngeal stenting (7 days of intubation or 1 month of Montgomery T-tube in previously tracheotomized patients) and endoscopic controls with possible additional balloon dilation every 15 days for at least 2 months.
Patients' ages ranged from 1 to 101 months. Postoperative follow-up ranged from 4 to 45 months (median value±SD: 15.3±11.9). The mean duration of the endoscopic procedure was 35.2±13.2 min. The number of days spent in PICU during the perioperative period varied between 2 and 15. Four patients (22.2%) needed one and 14 patients (77.7%) required several (from 4 to 7) additional balloon dilations during the postoperative endoscopic controls. No incident was observed during or immediately after EACS. Treatment was efficient in 83% of cases (n=15), with no residual respiratory symptoms and grade 0 to 1 SGS at the end of follow-up.
EACS is a safe and efficient technique to treat pediatric subglottic stenosis, regardless of their grade and length, provided to associate it with postoperative laryngeal stenting and regular endoscopic follow-up with possible additional balloon dilations. In our teams, it has become the first line treatment for most grades II to IV SGS. Its indications can be extended to congenital stenosis with cartilaginous involvement and to long-lasting acquired stenosis with firm fibrosis.
分析一种治疗小儿声门下狭窄的新内镜方法的疗效。
病例系列。
三级医疗中心。
2006年至2010年间,18例II至IV级小儿声门下狭窄病例(8例先天性,10例后天性)在我们机构接受了内镜下环状软骨前部劈开术(EACS)和球囊扩张术。治疗方案包括系统性术后喉部支架置入(插管7天或在先前已行气管切开术的患者中置入蒙哥马利T型管1个月),以及每15天进行一次内镜检查,并视情况进行额外的球囊扩张,至少持续2个月。
患者年龄从1个月至101个月不等。术后随访时间为4至45个月(中位数±标准差:15.3±11.9)。内镜手术的平均时长为35.2±13.2分钟。围手术期在儿科重症监护病房(PICU)的天数在2至15天之间。4例患者(22.2%)在术后内镜检查时需要进行1次额外的球囊扩张,14例患者(77.7%)需要进行数次(4至7次)额外的球囊扩张。在EACS期间或术后即刻未观察到任何不良事件。83%的病例(n = 15)治疗有效,随访结束时无残留呼吸症状,声门下狭窄分级为0至1级。
EACS是一种治疗小儿声门下狭窄的安全有效的技术,无论其分级和长度如何,前提是将其与术后喉部支架置入以及定期内镜随访并视情况进行额外的球囊扩张相结合。在我们的团队中,它已成为大多数II至IV级声门下狭窄的一线治疗方法。其适应证可扩展至累及软骨的先天性狭窄以及伴有坚实纤维化的长期后天性狭窄。