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磁疗膝关节包裹对骨关节炎患者关节本体感觉的影响:一项随机对照初步试验。

Influence of magnetic knee wraps on joint proprioception in individuals with osteoarthritis: a randomized controlled pilot trial.

机构信息

Department of Physical Therapy, College of Medicine, Chang Gung University, Taoyuan and Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Keelung, Taiwan.

出版信息

Clin Rehabil. 2011 Mar;25(3):228-37. doi: 10.1177/0269215510382849. Epub 2010 Oct 27.

Abstract

OBJECTIVE

To determine the effects of magnetic knee wraps (MKWs) on joint position sense (JPS) in individuals with mild-to-moderate knee osteoarthritis.

DESIGN

Randomized, double-blind, placebo-controlled pilot trial.

SETTING

Rehabilitation clinic of a tertiary hospital.

SUBJECTS

Fifty volunteers with mild-to-moderate knee osteoarthritis participated and 33 (66%) completed the trial; only one (2%) withdrew due to study-related adverse effects.

INTERVENTIONS

Knee wraps with a static magnetic field (35  mT) were compared with control knee wraps for 12 weeks.

MAIN MEASURES

The main outcome measure was JPS at first, fourth, and twelfth week while applying of the knee wrap, quantified as the ability to replicate target knee joint angles. The secondary outcome was the Comprehensive Osteoarthritis Test (COAT) total score.

RESULTS

In the intention-to-treat analysis with an alpha-level of 0.05, 12-week application of the MKWs did not significantly reduce the mean absolute error (MAE) of JPS (n = 18; P = 0.627); contrarily, the MAE was found to decrease significantly after wearing the sham MKWs (n = 20; P = 0.01). The COAT total score gradually improved in both groups (P < 0.05). When comparing the improvement of MAE and COAT total score at each follow-up between two groups, no significant differences were found; the maximal difference in the improvement of MAE between two groups was noted at week 12 (mean difference: 1.2°; 95% confidence interval -0.4 to 2.9; P = 0.144). In the per-protocol analysis, the study group showed better improvement in the COAT total score at week 12 (P = 0.033).

CONCLUSION

The 35-mT MKWs could not significantly influence knee JPS in individuals with mild-to-moderate knee osteoarthritis.

摘要

目的

确定磁膝带(MKW)对轻度至中度膝骨关节炎患者关节位置感(JPS)的影响。

设计

随机、双盲、安慰剂对照初步试验。

地点

一家三级医院的康复诊所。

受试者

50 名志愿者患有轻度至中度膝骨关节炎,其中 33 名(66%)完成了试验;只有 1 名(2%)因研究相关的不良反应而退出。

干预措施

用静态磁场(35 mT)比较膝带与对照膝带 12 周。

主要措施

主要观察指标为第一次、第四次和第十二周佩戴膝带时的 JPS,量化为复制目标膝关节角度的能力。次要结果是综合骨关节炎测试(COAT)总评分。

结果

在以 0.05 的α水平进行的意向治疗分析中,12 周应用 MKW 并未显著降低 JPS 的平均绝对误差(MAE)(n=18;P=0.627);相反,在佩戴假 MKW 后,MAE 显著降低(n=20;P=0.01)。两组的 COAT 总评分均逐渐改善(P<0.05)。当比较两组在每次随访时 MAE 和 COAT 总评分的改善情况时,未发现显著差异;两组 MAE 改善的最大差异出现在第 12 周(平均差异:1.2°;95%置信区间 -0.4 至 2.9;P=0.144)。在方案遵守分析中,研究组在第 12 周的 COAT 总评分改善更好(P=0.033)。

结论

35 mT 的 MKW 不能显著影响轻度至中度膝骨关节炎患者的膝关节 JPS。

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