Kim H J, Chung C H, Moon C O, Park C G, Hong S P, Oh M S, Carroll H J
Department of Internal Medicine, College of Medicine, Chosun University, Kwangju, Korea.
Korean J Intern Med. 1990 Jul;5(2):97-100. doi: 10.3904/kjim.1990.5.2.97.
The release of potassium from platelets is a well-known cause of pseudohyperkalemia in thrombocytosis. In predicting the magnitude of pseudohyperkalemia associated with thrombocytosis, previous investigations considered only the amount of potassium released from platelets during blood clotting, although the increment in serum potassium during blood clotting depends on the quantity of potassium released from platelets as well as the volume of distribution of the released potassium, which is inversely proportionate to the hematocrit. The present study proposes a new mathematical formula to predict the magnitude of increase in serum potassium during blood clotting, and accuracy of this formula has been tested in a patient with thrombocytosis.
血小板释放钾是血小板增多症中假性高钾血症的一个众所周知的原因。在预测与血小板增多症相关的假性高钾血症的严重程度时,以往的研究仅考虑了血液凝固过程中血小板释放的钾量,尽管血液凝固过程中血清钾的升高取决于血小板释放的钾量以及所释放钾的分布容积,而后者与血细胞比容成反比。本研究提出了一个新的数学公式来预测血液凝固过程中血清钾升高的程度,并且在一名血小板增多症患者中对该公式的准确性进行了测试。