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血小板增多症中假性高钾血症程度的决定因素。

Determinants of magnitude of pseudohyperkalemia in thrombocytosis.

作者信息

Kim H J, Chung C H, Moon C O, Park C G, Hong S P, Oh M S, Carroll H J

机构信息

Department of Internal Medicine, College of Medicine, Chosun University, Kwangju, Korea.

出版信息

Korean J Intern Med. 1990 Jul;5(2):97-100. doi: 10.3904/kjim.1990.5.2.97.

Abstract

The release of potassium from platelets is a well-known cause of pseudohyperkalemia in thrombocytosis. In predicting the magnitude of pseudohyperkalemia associated with thrombocytosis, previous investigations considered only the amount of potassium released from platelets during blood clotting, although the increment in serum potassium during blood clotting depends on the quantity of potassium released from platelets as well as the volume of distribution of the released potassium, which is inversely proportionate to the hematocrit. The present study proposes a new mathematical formula to predict the magnitude of increase in serum potassium during blood clotting, and accuracy of this formula has been tested in a patient with thrombocytosis.

摘要

血小板释放钾是血小板增多症中假性高钾血症的一个众所周知的原因。在预测与血小板增多症相关的假性高钾血症的严重程度时,以往的研究仅考虑了血液凝固过程中血小板释放的钾量,尽管血液凝固过程中血清钾的升高取决于血小板释放的钾量以及所释放钾的分布容积,而后者与血细胞比容成反比。本研究提出了一个新的数学公式来预测血液凝固过程中血清钾升高的程度,并且在一名血小板增多症患者中对该公式的准确性进行了测试。

相似文献

4
Thrombocytosis elevates serum potassium.血小板增多症会使血清钾升高。
Am J Kidney Dis. 1988 Aug;12(2):116-20. doi: 10.1016/s0272-6386(88)80005-2.

本文引用的文献

1
Pseudohyperkalemia with thrombocytosis.伴有血小板增多症的假性高钾血症。
N Engl J Med. 1962 Nov 1;267:895-900. doi: 10.1056/NEJM196211012671801.
2
Platelet function in thrombocythemia. The effect of platelets and serotonin on serum potassium and bilirubin.
Acta Med Scand. 1960 Aug 10;167:353-68. doi: 10.1111/j.0954-6820.1960.tb03558.x.
3
Hyperkalemia associated with the myeloproliferative disorder.与骨髓增殖性疾病相关的高钾血症。
Arch Intern Med. 1960 Oct;106:479-82. doi: 10.1001/archinte.1960.03820040017003.
5
Pseudohyperkalaemia - a cause of diagnostic confusion.
S Afr Med J. 1981 Dec 19;60(25):973-4.
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Pseudohyperkalemia due to release of potassium from white blood cells during clotting.
N Engl J Med. 1966 Feb 17;274(7):369-75. doi: 10.1056/NEJM196602172740702.
8
Pseudohyperkalaemia.假性高钾血症
Br Med J (Clin Res Ed). 1985 Sep 28;291(6499):890-1. doi: 10.1136/bmj.291.6499.890.

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