Vara-Thorbeck R, Morales O I, Rosell J, Gomez M
Neurochirurgische Abteilung der Chirurgischen Universitätsklinik Granada.
Zentralbl Neurochir. 1990;51(4):216-8.
Osteoblastoma of the spine is a rare but important cause of back pain and the sciatica syndrome in young adults. Osteoblastoma of the skull is rare and the involvement of the orbital roof is very unusual. Clinical complaints and physical examination are not specific enough to provide a lead to the diagnosis. Bone scans and computerized tomography scans should be performed in all cases, to show the extent of vertebrae or calvarium infiltration by the tumor. To prevent recurrence and malignant transformation, the tumor should be completely removed whenever possible. If tumor excision is incomplete, a continuous follow-up is necessary to detect any recurrence or malignant transformation, which normally appears 5-10 years after the first operation (in one of our cases 7 years later).
脊柱骨母细胞瘤是年轻成年人背痛和坐骨神经痛综合征的一种罕见但重要的病因。颅骨骨母细胞瘤罕见，眶顶受累非常少见。临床症状和体格检查不够特异，无法为诊断提供线索。所有病例均应进行骨扫描和计算机断层扫描，以显示肿瘤对椎骨或颅骨的浸润范围。为防止复发和恶变，应尽可能彻底切除肿瘤。如果肿瘤切除不完全，则需要持续随访以检测任何复发或恶变情况，复发或恶变通常在首次手术后5至10年出现（我们的一个病例是7年后）。
