Wang M T, Li Y Z, Zhao T Z, Ji C R, Feng W S, Liu Y Z
Henan Institute of Chemistry, Zhengzhou.
Yao Xue Xue Bao. 1990;25(11):866-8.
A new (-)-4-oxo-2,6-bis-(3',4'-methylenedioxy phenyl)-3, 7-dioxabicyclo[3, 3, 0] octane lignan, genkdaphin was isolated from the leaves of Daphne genkwa Sieb. et Zucc. mp 118-119.5 degrees C, C20H16O7 (HRMS, 368.08631, M+), [alpha]27D-64.8 degrees (c 0.5, CHCl3). On the basis of UV, IR, MS, 1H and 13CNMR spectral analysis, the structure of the genkdaphin has been established as (-)-4-oxosesamin.
从芫花（Daphne genkwa Sieb. et Zucc.）叶中分离出一种新的（-）-4-氧代-2,6-双-（3',4'-亚甲二氧基苯基）-3,7-二氧杂双环[3,3,0]辛烷木脂素，即芫花素。熔点118 - 119.5℃，C20H16O7（高分辨质谱，368.08631，M⁺），[α]27D - 64.8°（c 0.5，氯仿）。基于紫外、红外、质谱、¹H和¹³C核磁共振光谱分析，芫花素的结构已确定为（-）-4-氧代芝麻素。
