Khristeva V, Khristova N, Mikhaĭlova A, Mukhtarova M, Benchev I, Kasŭrov M
Probl Khig. 1990;15:75-85.
On the basis of job characteristics of workers from the production "ethylene", chronometric studies and measurement of concentration from chemical compounds are developed professional diagrams and risk diagrams, which give a possibility for more precise account of the exposure to chemical noxious compounds (by figures). According to the values of the estimated total index of exposure 156 workers are distributed in 5 groups. Besides, 48 workers with prolonged length of service in the production and 37 persons control group are examined. The toxicological, haematological and biochemical indices are studied and the neuro-vegetative status traced. Mainly in the groups with high chemical exposure (first and second risk groups) and with prolonged length of service are established high per cent of workers with deviation in the examined indices, which give grounds to assert for the presence of dose-response relationship.
根据“乙烯”生产工人的工作特点，开展了计时研究和化合物浓度测量，绘制了专业图表和风险图表，从而能够更精确地计算化学有害化合物的暴露量（以数据表示）。根据估计的总暴露指数值，156名工人被分为5组。此外，还对48名生产年限较长的工人和37名对照组人员进行了检查。研究了毒理学、血液学和生化指标，并追踪了神经植物状态。主要在化学暴露高的组（第一和第二风险组）以及生产年限较长的组中，发现有较高比例的工人检查指标出现偏差，这为存在剂量反应关系提供了依据。
