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中子俘获治疗药物研发中硼分析技术综述。

A review of techniques for the analysis of boron in the development of neutron capture therapy agents.

作者信息

Moore D E

机构信息

Department of Pharmacy, University of Sydney, Australia.

出版信息

J Pharm Biomed Anal. 1990;8(7):547-53. doi: 10.1016/0731-7085(90)80078-4.

DOI:10.1016/0731-7085(90)80078-4
PMID:2100215
Abstract

The resurgence of interest in neutron capture therapy, which uses boron-10 labelled compounds and neutron irradiation as a technique for the treatment of cancer, has been accompanied by the application of a new generation of techniques for the analysis and imaging of boron in biological matrices. In this review, a description is given of the requirements for boron neutron capture agents and the achievements to date of the analytical techniques.

摘要

对中子俘获疗法的兴趣再度兴起,该疗法使用硼 - 10标记化合物和中子辐照作为治疗癌症的技术,与此同时,新一代用于分析生物基质中硼以及对其成像的技术也得到了应用。在本综述中,阐述了硼中子俘获剂的要求以及分析技术目前所取得的成果。

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引用本文的文献

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New drugs for BNCT: an experimental approach.用于硼中子俘获疗法的新药:一种实验方法。
Strahlenther Onkol. 1999 Jun;175 Suppl 2:118-20. doi: 10.1007/BF03038909.
2
Fourier transform infrared (FTIR) spectrometry for the assay of polyhedral boron compounds in plasma and pharmaceutical formulations.
Pharm Res. 1994 May;11(5):723-8. doi: 10.1023/a:1018984414803.