Langford A
Poliklinik für Zahn-, Mund- und Kieferheilkunde Nord, Freie Universität Berlin.
Parodontol. 1990 May;1(2):119-32.
During HIV infection different lesions may occur in the area of the gingiva and/or the periodontium. An increased frequency and severity of periodontal diseases has been observed. Different forms of Candida albicans infection have been clinically characterized as pseudomembranous, erythematous (atrophic) or hyperplastic form or as papillary variant. While infection with Candida albicans may occur frequently in other areas of the oral mucosa, candidiasis of the gingiva seems to be quite rare. Due to the underlying immunodeficiency, HIV-infected patients are prone to infection with and/or reactivation of different viruses, which may cause oral lesions as well. Recurrent progressive ulcerations may occur due to herpes simplex virus 1/2, while ulcerations with a punched-out appearance may result from disseminated CMV infection. Oral Kaposi's sarcoma may clinically present as bluish or red spots, which may increase into exophytic tumors during the progress of the disease.
在HIV感染期间,牙龈和/或牙周区域可能会出现不同的病变。已观察到牙周疾病的发生频率和严重程度有所增加。白色念珠菌感染的不同形式在临床上表现为假膜型、红斑(萎缩)型或增生型,或乳头状变体。虽然白色念珠菌感染在口腔黏膜的其他区域可能经常发生,但牙龈念珠菌病似乎相当罕见。由于潜在的免疫缺陷,HIV感染患者容易感染和/或重新激活不同的病毒,这也可能导致口腔病变。单纯疱疹病毒1/2可引起复发性进行性溃疡,而播散性巨细胞病毒感染可能导致出现边缘整齐的溃疡。口腔卡波西肉瘤在临床上可能表现为蓝色或红色斑点,在疾病进展过程中可能发展为外生性肿瘤。