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[药物预防 Mendelson 综合征对新生儿的潜在影响]

[Possible effects of pharmacologic prophylaxis for Mendelson's syndrome on newborns].

作者信息

Bifarini G, Trabalza N, Falconi S, Malà L, Favetta P

机构信息

Istituto di Anestesiologia e Rianimazione, Università degli Studi di Perugia.

出版信息

Minerva Anestesiol. 1990 Dec;56(12):1447-50.

PMID:2100324
Abstract

Forty-eight newborn infants whose mothers underwent both elective and urgent caesarean section were studied. Mothers were randomly assigned to one of the treatment groups for the prophylaxis of Aspiration Pneumonitis: group A was treated with ranitidine, 50 mg i.v.; group B with ranitidine, 50 mg, and metoclopramide, 10 mg i.v.; group C no medication. Neonatal assessment included Apgar score and various haematological laboratory tests: haemogasanalysis, glycemia, electrolites, hematocrit, hemoglobin, bilirubinemia, SGOT, SGPT. Nor clinical or statistic differences were noted among the three infant groups.

摘要

对48名母亲接受择期和急诊剖宫产的新生儿进行了研究。母亲们被随机分配到预防吸入性肺炎的治疗组之一:A组静脉注射50毫克雷尼替丁;B组静脉注射50毫克雷尼替丁和10毫克甲氧氯普胺;C组不使用药物。新生儿评估包括阿氏评分和各种血液学实验室检查:血气分析、血糖、电解质、血细胞比容、血红蛋白、胆红素血症、谷草转氨酶、谷丙转氨酶。三组婴儿之间未发现临床或统计学差异。

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