Günay H, Evers B G
Zentrum Zahn-, Mund- und Kieferheilkunde Medizinische Hochschule Hannover.
Parodontol. 1990 Nov;1(4):329-42.
In the present study a newly developed concept for avoiding recurrences after the periodontal surgical treatment of cyclosporin A-induced gingival hyperplasia is described. Conventional gingivectomy results in restitutio per secundam, which promotes recurrences. To avoid this we tried to achieve a restitutio per primam by using a modified surgical technique. Ten patients, four treated under general anesthesia and six on an outpatient basis, were treated with this technique. Patients were monitored for 20 month. Pre- and postoperative care was performed in a standardized manner for all patients. During the surveillance, a long-term suppression of the cyclosporin-induced gingival hyperplasia could be found, but it was not possible to avoid recurrences totally.
在本研究中，描述了一种新开发的概念，用于避免环孢素A诱导的牙龈增生牙周手术治疗后的复发。传统的牙龈切除术会导致二期愈合，这会促进复发。为避免这种情况，我们尝试通过使用改良的手术技术来实现一期愈合。十名患者，四名在全身麻醉下接受治疗，六名门诊治疗，采用该技术进行治疗。对患者进行了20个月的监测。所有患者均以标准化方式进行术前和术后护理。在监测期间，可以发现环孢素诱导的牙龈增生得到了长期抑制，但不可能完全避免复发。
