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色素性视网膜炎合并青光眼——临床分析

Retinitis pigmentosa associated with glaucoma--clinical analysis.

作者信息

Peng T, Wu L, Zhou W

机构信息

Zhongshan Ophthalmic Centre, Sun Yat-san University of Medical Sciences, Guangzhou, China.

出版信息

Yan Ke Xue Bao. 1990 Jun;6(1-2):17-9.

PMID:2101353
Abstract

A clinical analysis of Retinitis Pigmentosa (RP) was made in 2,789 eyes of 1,400 patients seen over a 5 year period (1983-1987), 64 eyes of 32 cases (2.3%) of RP associated with glaucoma were investigated. Of these 32 cases, the angle closure glaucoma was much more than the open angle glaucoma (30/2). More than half of the 32 cases were without cupping of disk, 5 cases did not have the glaucomatous damage to disk in spite of persistent elevated intraocular pressure for 0.5-5 yrs under the maximum medical therapy. 31 cases (97%) had subnormal blood pressure compared with the normal blood pressure value in different age groups. Histopathologic changes of the trabecular meshwork (TM) of 14 eyes showed a little bit more pigment cells in the TM than normal subjects, no typical features that would obstruct the outflow channels.

摘要

对1983年至1987年这5年间诊治的1400例患者的2789只眼睛进行了色素性视网膜炎(RP)的临床分析,其中对32例(2.3%)伴有青光眼的RP患者的64只眼睛进行了研究。在这32例患者中,闭角型青光眼比开角型青光眼多得多(30/2)。32例患者中半数以上视盘无杯状凹陷,5例患者尽管在最大药物治疗下眼压持续升高0.5至5年,但视盘未出现青光眼性损害。与不同年龄组的正常血压值相比,31例(97%)患者血压低于正常。对14只眼睛小梁网(TM)的组织病理学检查显示,TM中的色素细胞比正常受试者略多,没有阻碍房水流出通道的典型特征。

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